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目的:观察整合医学诊疗模式治疗脑卒中后抑郁及对外周血神经递质水平的影响。方法:将200例PSD患者随机分为西药组、中药组、针刺组、心理组、整合组。治疗8周后采用汉密尔顿抑郁量表(HAMD)、美国国立卫生研究院卒中量表(NIHSS)、日常生活活动能力量表Barthel指数评定临床疗效。结果:整合组疗效优于其余4组(P<0.05);整合组在改善患者HAMD、NIHSS、Barthel指数、神经递质方面显著优于其余4组(P<0.01)。结论:整合医学诊疗模式可以明显改善PSD患者的抑郁症状、神经功能缺损症状,提高患者生活质量,促进患者全面康复。
Objective: To observe the effect of integrated medical diagnosis and treatment on post-stroke depression and neurotransmitter levels in peripheral blood. Methods: 200 patients with PSD were randomly divided into western medicine group, traditional Chinese medicine group, acupuncture group, psychological group and integration group. After 8 weeks of treatment, the clinical efficacy was assessed using the Hamilton Depression Rating Scale (HAMD), the National Institutes of Health Stroke Scale (NIHSS) and the Barthel Index of Daily Living Activity Scale. Results: The efficacy of the integrated group was better than that of the other 4 groups (P <0.05). The integrated group was significantly better than the other 4 groups in improving HAMD, NIHSS, Barthel index and neurotransmitter (P <0.01). Conclusion: The integration of medical diagnosis and treatment model can significantly improve the symptoms of depression, neurological deficits in PSD patients, improve the quality of life of patients, and promote the comprehensive rehabilitation of patients.