目的　考察温度对 1%硫酸阿托品滴眼剂稳定性影响。方法　将浓度为 1%硫酸阿托品滴眼剂分别存放于 0℃～ 30℃、30± 2℃、40± 2℃、5 0± 2℃条件下 ,按一定时间间隔取样测定含量、pH值。 结果　随着存放温度的上升 ,1%硫酸阿托品滴眼剂稳定性 (含量、pH值 )下降。 结论　 1%硫酸阿托品滴眼剂应在2 8℃以下的条件存放较为适宜。 Objective To investigate the effect of temperature on the stability of 1% atropine sulfate eye drops. Methods The concentration of 1% atropine sulfate eye drops were stored at 0 ℃ ~ 30 ℃, 30 ± 2 ℃, 40 ± 2 ℃, 5 0 ± 2 ℃ under the conditions of sampling at regular intervals to determine the content, pH value. Results As the storage temperature increased, 1% atropine sulfate eye drops stability (content, pH) decreased. Conclusion 1% atropine eye drops should be stored under the conditions of 2 8 ℃ is more appropriate.