实验兔３０只平均分三组：Ａ组饲正常饲料，Ｂ组饲含１．２％胆固醇和０．５％胆盐的高胆固醇饲料，Ｃ组饲高胆固醇饲料和乙醇。乙醇提供总热卡的３０％。一个月后抽血测甘油三酯及胆固醇，并剖腹取胆囊及肝胆管胆汁，观察胆囊成石率和测各种胆汁成分。结果：Ｃ组胆囊内无结石形成，血清胆固醇和胆囊胆汁中的胆固醇、磷脂、钙等明显低于Ｂ组，提示乙醇对胆囊胆固醇结石有预防作用 30 rabbits were equally divided into three groups: group A was fed normal diet, group B was fed with high cholesterol diet containing 1.2% cholesterol and 0.5% bile salt, group C was fed with high cholesterol diet and ethanol. Ethanol provides 30% of the total calories. One month later, blood was collected to measure triglyceride and cholesterol. Caesarean sections and gallbladder bile were obtained by cesarean section. The rate of gallstone formation and bile composition were measured. Results: There were no gallstones in group C, and cholesterol, phospholipid and calcium in serum cholesterol and gallbladder were significantly lower than those in group B, which suggested that ethanol could prevent gallstone gallstone in gallbladder