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γ- 氨基丁酸是中枢神经系统的抑制性神经递质,但在生理条件下,γ- 氨基丁酸的通透性较差,常通过其衍生物增强 γ- 氨基丁酸的生理活性,作者以γ- 氨基丁酸为原料合成了新γ- 氨基丁酸的载体化合物[4- (2,4—二羟基苯次甲氨基)丁酸酯],并经元素分析、红外光谱和核磁共振谱验证这些化合物的结构
GABA is an inhibitory neurotransmitter in the central nervous system, but under physiological conditions, γ-aminobutyric acid has poor permeability and often enhances the physiological activity of γ-aminobutyric acid by its derivatives. The new γ-aminobutyric acid carrier compound [4- (2,4-dihydroxybenzylmethylamino) butyrate] was synthesized from γ-aminobutyric acid and characterized by elemental analysis, infrared spectroscopy and nuclear magnetic resonance Verify the structure of these compounds