论文部分内容阅读
中性白细胞的细胞浆抗体(ANCA)是韦格内氏肉芽肿和微小多动脉炎的标记物,具有较高的敏感性和特异性,在其他血管炎疾患中也发现了ANCA,常发生于少数囊性纤维化(CF)伴血管炎的患者。而Finnegan 等认为急性或慢性胸部感染与ANCA 之间无任何关系。作者新近对15例儿童(男9、女6例,平均年龄8.3岁)和15例成人(男8、女7例,平均年龄22.4岁)检测了CF 感染加重期间的血清ANCA 滴度.用间接免疫荧光法检测乙醇固定的ANCA。结果,绝大多数中性白细胞的细胞浆示明显荧光为阳性。对每
Neutrophil cytoplasmic antibodies (ANCA) are markers of Wegener’s granulomatosis and micro-polyarteritis with high sensitivity and specificity. ANCA has also been found in other vasculitides and often occurs in A small number of patients with cystic fibrosis (CF) with vasculitis. Finnegan et al. Conclude that there is no relationship between acute and chronic chest infections and ANCA. The authors recently tested for serum ANCA titres in 15 children (9 males and 6 females, mean age 8.3 years) and 15 adults (8 males and 7 females, mean age 22.4 years) with increased CF infection. Immunofluorescence was used to detect ethanol-fixed ANCA. As a result, the vast majority of neutrophils show clear positive cytoplasm fluorescence. For each