全身炎症反应综合征(systemic inflammatoryresponse syndrome,SIRS)是20世纪90年代提出的新概念,指当各种严重感染、创伤、烧伤、缺氧及再灌注损伤等感染与非感染等因素作用于机体,神经内分泌和免疫系统被激活,释放出许多炎性递质及细胞因子导致不同程度的应激和炎症反应,造成早期器官功能障碍,如病情继续进展或病损再次侵袭,则早期的炎症反应可因瀑布样级联反应使炎症失控 Systemic inflammatory response syndrome (SIRS) is a new concept put forward in the 1990s. It refers to the role of systemic inflammatory response syndrome (SIRS) in the body when a variety of infections such as severe infection, trauma, burn, hypoxia and reperfusion injury, Neuroendocrine and immune system is activated, release of many inflammatory neurotransmitters and cytokines lead to varying degrees of stress and inflammatory response, resulting in early organ dysfunction, such as the disease continues to progress or re-invasion of lesions, the early inflammatory response can be Cascade reaction cascades the inflammation out of control