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肺癌发病率和死亡率呈逐年上升趋势、５年生存率仅１０％左右。肺癌的早期诊断有重要意义。笔者应用荧光对１１０例肺癌患者、１００例肺良性疾病患者和３５例正常人的血清进行检测。分析其荧光光谱。以波长６２５ｎｍ处的荧光强度大于波长６１５ｎｍ处为阳性，小于者为阴性，肺癌组阳性７７例（７０％），肺良性疾病组阳性１６例（１６％），健康对照组２例（５．７１％）阳性，肺癌组阳性率明显高于肺良性疾病组（Ｐ＜０．０１）和健康对照组（Ｐ＜０．０１）；不同组织类型的肺癌阳性率不同、腺癌阳性率最高８７．８８％，鳞癌次之６７．６５％，小细胞癌５０％。上述结果表明，应用荧光光谱分析对肺癌（尤其是非小细胞肺癌）的诊断，甚至早期诊断有重要参考价值。
The incidence and mortality of lung cancer have been increasing year by year, and the 5-year survival rate is only about 10%. The early diagnosis of lung cancer is of great significance. The authors used fluorescence to detect the serum of 110 patients with lung cancer, 100 patients with benign lung disease, and 35 normal people. Analyze its fluorescence spectrum. The fluorescence intensity at the wavelength of 625 nm was greater than that at the wavelength of 615 nm, and the lesser was negative. The lung cancer group was positive in 77 cases (70%), the benign lung disease group in 16 cases (16%), and the healthy control group in 2 cases (5.71). The positive rate of lung cancer was significantly higher in the lung cancer group than in the benign lung disease group (P <0.01) and the healthy control group (P <0.01). The positive rate of lung cancer was different in different tissue types and the highest positive rate of adenocarcinoma was 87. 88%, followed by 67.65% of squamous cell carcinoma and 50% of small cell carcinoma. The above results show that the application of fluorescence spectrum analysis has important reference value for the diagnosis and even early diagnosis of lung cancer (especially non-small cell lung cancer).