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胃粘膜能分泌两种不同免疫原性的胃蛋白酶原(PG),即胃蛋白酶原Ⅰ和Ⅱ(PGI和PGII)。血清PGI水平为估计壁细胞功能状态十分有用的参数。但门腔分流对肝硬化患者的PGI基础水平和经五肽胃泌素刺激后壁细胞分泌能力的影响仍未弄清。本文旨在研究已行门腔分流术和未行这种手木的肝硬化患者在基础状态和五肽胃泌素刺激后胃酸及PGI的分泌能力。病例及方法:研究对象包括经皮肝穿活检由组织学证实的27例肝硬化患者,其中13例因食管静脉曲张致
Gastric mucosa secretes two different immunogenic pepsinogen (PG), namely pepsinogen I and II (PGI and PGII). Serum PGI levels are useful parameters for estimating parietal cell function status. However, the effect of portal shunt on the basal level of PGI and the secretory capacity of parietal cells after pentagastrin stimulation in patients with cirrhosis remains unclear. This study aimed to investigate the secreted capacity of gastric acid and PGI after basal ganglia and pentagastrin stimulation in patients with cirrhotic patients who had undergone portal shunt and those who did not. Cases and Methods: The subjects included histologically confirmed percutaneous transhepatic biopsy in 27 patients with cirrhosis, of which 13 were caused by esophageal varices