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在水溶液中,DNA以微观的形态存在,由于布朗运动以及DNA之间的相互作用的存在,使得DNA的浓度可能影响着DNA的微观分布,从而影响DNA损伤,这在我们以前的实验中已有了初步的观测与发现。关于DNA浓度对DNA损伤的影响的报道很少,实验结果不统一,也不系统,且以前的报道均为低LET射线辐射后的结果。关于高LET的重离子的研究目前尚未见诸报道。
In aqueous solution, DNA exists in microscopic form. Due to the Brownian motion and the interaction between DNA, the concentration of DNA may affect the microscopic distribution of DNA and thus DNA damage, which has been found in our previous experiments The initial observations and findings. There are few reports on the effects of DNA concentration on DNA damage, the results are not uniform or systematic, and the previous reports are the result of low LET radiation. Research on heavy LET heavy ions has not been reported yet.