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目的探讨曲美他嗪联合阿托伐他汀钙在缺血性心肌病心力衰竭临床治疗中的应用效果。方法选择缺血性心肌病心力衰竭患者102例,随机分为研究组与对照组,每组51例。对照组给予常规治疗,研究组给予曲美他嗪联合阿托伐他汀钙治疗。观察2组临床疗效及心脏超声检查结果。结果研究组总有效率为96.08%,高于对照组的80.39%,差异有统计学意义(P<0.05)。研究组左心室射血分数、心排出量高于对照组,心室收缩末期内径及舒张末期内径低于对照组,差异有统计学意义(P<0.05)。结论曲美他嗪联合阿托伐他汀钙治疗缺血性心肌病心力衰竭临床疗效好。
Objective To investigate the effect of trimetazidine combined with atorvastatin calcium in the clinical treatment of ischemic cardiomyopathy heart failure. Methods 102 cases of ischemic cardiomyopathy heart failure patients were randomly divided into study group and control group, 51 cases in each group. The control group was given routine treatment, and the study group was given trimetazidine combined with atorvastatin calcium treatment. The clinical efficacy and echocardiographic results of the two groups were observed. Results The total effective rate of the study group was 96.08%, which was higher than that of the control group (80.39%), the difference was statistically significant (P <0.05). The left ventricular ejection fraction and cardiac output in the study group were significantly higher than those in the control group. The end-systolic and diastolic diameters of the study group were lower than those of the control group (P <0.05). Conclusion Trimetazidine combined with atorvastatin calcium is effective in treating heart failure with ischemic cardiomyopathy.