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目的:探讨复方肾炎片联合贝那普利治疗慢性肾小球肾炎的临床疗效及安全性。方法:将我院收治的40例慢性肾小球肾炎患者随机分为治疗组(20例)和对照组(20例),治疗组给予复方肾炎片联合贝那普利治疗,对照组仅单纯给予复方肾炎片治疗,比较2组患者的临床疗效。结果:治疗组患者的总有效率为100%,对照组患者的总有效率为70%,治疗组显著高于对照组,2组比较,差异具有统计学意义(P<0.05)。结论:复方肾炎片联合贝那普利治疗慢性肾小球肾炎的临床疗效显著,药物安全有效,对肝肾功能影响小,不良反应少,值得临床推广应用。
Objective: To investigate the clinical efficacy and safety of compound nephritis tablets combined with benazepril in the treatment of chronic glomerulonephritis. Methods: Forty patients with chronic glomerulonephritis admitted to our hospital were randomly divided into treatment group (n = 20) and control group (n = 20). The treatment group received compound nephritis tablets combined with benazepril treatment while the control group only Compound nephritis tablets treatment, the clinical efficacy of two groups were compared. Results: The total effective rate was 100% in the treatment group and 70% in the control group, which was significantly higher in the treatment group than in the control group. The difference was statistically significant (P <0.05). Conclusion: The compound nephritis tablets combined with benazepril in the treatment of chronic glomerulonephritis significant clinical efficacy, drug safety and efficacy, little effect on liver and kidney function, fewer adverse reactions, worthy of clinical application.