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采用免疫组化ＡＢＣ法，对４５例随机采样的乙型肝炎患者行胃粘膜活检，作ＨＢｃＡｓ检测。结果：乙型肝炎患者胃粘膜中有ＨＢｃＡｇ存在，主要呈弥漫胞浆型分布，腺腔和胃小凹及间质中也可见ＨＢｃＡｇ颗粒；血清中ＨＢＶ单项或多项阳性者，胃粘膜ＨＢｃＡｇ阳性率相近（７５～８０％）；各类型肝炎患者胃粘膜ＨＢｃＡｇ阳性率比较：ＣＡＨ＞ＣＰＨ＞ＰＨＬＣ。提示：胃粘膜中有ＨＢｃＡｇ存在，可能胃粘膜能复制ＨＢＶ。
Using immunohistochemical ABC method, 45 cases of randomly sampled patients with hepatitis B gastric biopsy for HBcAs detection. Results: There were HBcAg in the gastric mucosa of patients with hepatitis B, mainly distributed in diffuse cytoplasm, HBcAg particles were also observed in the glandular cavity, gastric cavity and interstitium. The serum HBV single or multiple positive, gastric mucosa HBcAg positive (75-80%). The positive rates of HBcAg in gastric mucosa of various types of hepatitis were compared: CAH> CPH> PHLC. Tip: there is HBcAg gastric mucosa, gastric mucosa may replicate HBV.