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肿瘤相关性疲劳（ CRF）是影响肿瘤患者生活质量的最主要因素之一，其发病机制复杂。现代医学认为，CRF的发病机制涉及多脏器、多系统、多途径，主要与炎症标志物相关，治疗多为纠正贫血、兴奋中枢。中医则将其归于“虚劳”的范畴，病机涉及气血阴阳失衡，与脾胃肾密切联系，治疗予以补益气血、活血散瘀、健脾补肾。该文希望通过总结前人在 CRF上的研究，引起社会对 CRF治疗的重视，并关注如何提高CRF患者的生活质量。“,”Cancer related fatigue(CRF) is one of the most important factors affecting the quality of life of cancer patients,which has complex pathogenesis.Modern medicine believes that the pathogenesis of CRF involves multiple organs,multisystems and multipathways,mainly related to inflammatory markers.Treatment methods are to correct anemia and excite central nervous system .Traditional Chinese medicine attributes it to the category of ″consumptive disease″,pathogenesis involving the imbalance among Qi,blood,Yin and Yang, closely associated with spleen,stomach and kidney.Treatment methods are to reinforce Qi-Blood,activate blood circulation to dissipate blood stasis,strengthen spleen and kidney.Here hopes to summarize the previ-ous studies in CRF,to raise due attention of the society for the treatment of CRF ,and pay attention to how to improve the quality of life of CRF patients.