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[目的]对医院制剂“复方鱼鹅滴鼻剂”进行抗炎作用研究。[方法]实验采用二甲苯诱发小鼠耳廓肿胀法、大鼠棉球肉芽肿法研究其抗炎作用;通过抑制毛细血管通透性试验,观察“鱼鹅汤”对小鼠毛细管通透性的影响。[结果]“复方鱼鹅滴鼻剂”能明显降低二甲苯致小鼠耳肿胀的肿胀率和大鼠棉球肉芽肿的重量,具有减轻小鼠耳肿胀和抑制大鼠肉芽组织增生的作用,能提高小鼠毛细管通透性。[结论]医院制剂“复方鱼鹅滴鼻剂”能明显抑制急慢性炎症,提高毛细管通透性,缓解急慢性鼻炎症状。
[Objective] To study the anti-inflammatory effect of hospital preparation “compound fish and goose nasal drops”. [Methods] Xylene-induced mouse ear swelling method and cotton ball granuloma were used to study the anti-inflammatory effect. By inhibiting the capillary permeability test, The impact of permeability. [Result] The compound yunnane nasal drops significantly reduced the swelling rate of xylene-induced ear swelling and the weight of rat granuloma caused by xylene, relieved ear swelling and inhibited the proliferation of rat granulation tissue Role, can improve mouse capillary permeability. [Conclusion] The hospital preparation “compound fish goose nasal drops” can significantly inhibit acute and chronic inflammation, improve capillary permeability and relieve the symptoms of acute and chronic rhinitis.