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目的:探讨牙周健康状况对慢性阻塞性肺病急性加重的影响。方法:对呼吸内科住院的81例慢性阻塞性肺病伴有慢性牙周炎的患者随机分成两组,实验组在接受慢性阻塞性肺病规范化治疗的同时进行牙周非手术治疗,对照组只接受慢性阻塞性肺病规范化治疗,不予以牙周病治疗,随访1年,测量并比较患者牙周治疗前、后的菌斑指数(PLI)、龈沟出血指数(SBI)、牙周探诊深度(PD)、牙周附着水平(AL)、FEV1/FVC、FEV 1%pred.、急性加重次数,对急性加重次数与牙周健康指数行相关分析和多元线性逐步回归分析。结果:实验组牙周健康指数明显优于对照组(P<0.05),且急性加重次数低于对照组(P<0.05);牙周健康指数PLI、SBI、PD、AL与急性加重次数呈显著正相关(分别r=0.864,r=0.866,r=0.926,r=0.905),多元线性逐步回归分析显示急性加重次数与PD、PLI呈正相关。结论:改善慢性阻塞性肺病患者的牙周健康状况,可以降低患者的急性发作频率。
Objective: To investigate the effect of periodontal health on acute exacerbations of chronic obstructive pulmonary disease. Methods: Eighty-one patients with chronic obstructive pulmonary disease and chronic periodontitis hospitalized in respiratory medicine were randomly divided into two groups. The experimental group received periodontal non-surgical treatment while undergoing standardized treatment of chronic obstructive pulmonary disease. The control group received only chronic The standardization treatment of obstructive pulmonary disease was not treated by periodontal disease. The patients were followed up for 1 year. The PLI, SBI, PD ), Periodontal attachment (AL), FEV1 / FVC, FEV 1% pred., Acute exacerbations, correlation analysis and multiple linear stepwise regression analysis between the number of acute exacerbations and periodontal health index. Results: The periodontal health index of the experimental group was significantly higher than that of the control group (P <0.05), and the number of acute exacerbations was lower than that of the control group (P <0.05). The PLI, SBI, PD, AL and acute exacerbation (R = 0.864, r = 0.866, r = 0.926, r = 0.905 respectively). Multiple linear stepwise regression analysis showed that the number of acute exacerbations was positively correlated with PD and PLI. Conclusion: Improving the periodontal health of patients with chronic obstructive pulmonary disease can reduce the frequency of acute episodes.