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各种病因所致慢性肝病的共同病理过程为肝组织慢性炎症、纤维化,终末期形成肝硬变,部分患者发生癌变.明确诊断各种慢性肝病的不同阶段对于指导临床治疗及估计预后具有重要意义.目前有关肝病诊断的血清学指标不少,但多缺乏特异性.我们观察肝病患者55例及健康体检者20例血清透明质酸(hyaluronic acid.HA)及Ⅳ型胶原含量的变化,以探讨联合检测 HA 及Ⅳ胶原在肝病临床诊治中的意义.1 材料和方法1.1 材料本院门诊、住院肝病患者55例,正常对照20例为健康检查者.慢性肝炎患者32例(按1990年第六次全国病毒性肝炎会议修订的临床诊断标准),男20例,女12例,年龄
A variety of causes of chronic liver disease common pathological process of chronic inflammation of the liver tissue, fibrosis, the formation of cirrhosis at the end of the stage, some patients with cancer.Development of a clear diagnosis of various stages of chronic liver disease for the guidance of clinical treatment and prognosis is important Significance.At present, there are many serological indicators about the diagnosis of liver disease, but many lack specificity.We observed the changes of serum hyaluronic acid (HA) and typeⅣcollagen in 55 cases of liver disease and 20 healthy subjects, To explore the significance of joint detection of HA and Ⅳ collagen in the clinical diagnosis and treatment of liver disease.Materials and Methods1.1 MaterialsIn this hospital, 55 cases of outpatient liver disease, 20 cases of normal control for the health check-up.Chronic hepatitis patients 32 cases (according to 1990 Six national clinical revision of viral hepatitis meeting diagnostic criteria), 20 males and 12 females, age