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作者对急性梭曼中毒小鼠淋巴细胞增殖能力的影响进行动态观察,并探讨了中毒剂量及血胆碱酯酶活力与淋巴细胞增殖能力之间的关系。实验采用BALB/C纯系小鼠随机分为对照组与中毒Ⅰ、Ⅱ、Ⅲ组等4个组,对照组动物于背部皮下注射生理盐水0.1ml/10g体重,梭曼中毒组剂量为Ⅰ组154μg/kg,Ⅱ组96μg/kg、Ⅲ组38.4μg/kg注射与对照组同部位。分别于给毒后1、3、5、7、10天眼眶取血测全血胆碱
The authors observed the effects of acute soman intoxication mice lymphocyte proliferation ability, and explored the relationship between toxic dose and the activity of blood cholinesterase and lymphocyte proliferation. In the experiment, BALB / C mice were randomly divided into four groups: control group and poisoned group Ⅰ, Ⅱ and Ⅲ. The control animals were subcutaneously injected with 0.1 ml / 10 g physiological saline in the back, and the dose of soman intoxication group Ⅰ 154μg / kg, Ⅱ group 96μg / kg, Ⅲ group 38.4μg / kg injection with the same place in the control group. Respectively to the poison after 1, 3, 5, 7, 10 days to take blood orbital blood of whole blood choline