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目的研究氯胺酮和速眠新Ⅱ复合麻醉方法用于巴马小型猪实验的麻醉效果,初步观察复合麻药对动物机能指标的影响。方法使用氯胺酮和速眠新Ⅱ按2∶1.5(m L)的体积制成混合麻醉剂,在0.3—0.5 m L/kg的剂量范围内,给予动物一定剂量的麻药进行麻醉,记录麻药剂量、麻醉效果和生理指标。结果随着麻醉剂量的增加,麻药起效时间、肌松时间和眼睑反射消失时间均降低;动物心率和呼吸频率增加,对血压影响不大。结论 0.3—0.4m L/kg可以作为安全剂量用于小型猪的麻醉,不但起到良好的麻醉效果,对生理指标影响也不大。
Objective To study the anesthetic effect of ketamine combined with compound hypnotic Ⅱ in anesthesia with Bama miniature pigs and to observe the effects of compound anesthetics on animal performance. Methods Ketamine and hypnotic Ⅱ were mixed anesthesia in the volume of 2: 1.5 (m L), and the animals were given a certain dose of anesthetic for anesthesia in the dose range of 0.3-0.5 m L / kg. The anesthetic dosage was recorded and anesthesia was recorded Effect and physiological indicators. Results With the increase of anesthetic dose, the onset time of anesthetic, the relaxation time of eyelid and the disappearance of eyelid reflex were all decreased. The heart rate and respiratory rate of animals increased, which had little effect on blood pressure. Conclusion 0.3-0.4m L / kg can be used as a safe dose for anesthesia in miniature pigs, which not only plays a good anesthetic effect but also has little effect on physiological indexes.