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目的:观察早期大承气汤灌肠联合肠内营养对重症急性胰腺炎的疗效。方法:将2009年1月~2012年12月本院消化内科收治的重症急性胰腺炎患者140例纳入研究对象,给予禁食、胃肠减压、补液、抗感染等常规治疗,并采用随机数表法分为给予早期大承气汤灌肠联合肠内营养治疗的观察组和仅给予肠内营养治疗的对照组各70例,观察治疗后临床症状、体征缓解时间以及炎症因子水平。结果:观察组患者的体温恢复时间、腹痛缓解时间、腹胀消失时间、肛门排气时间均明显短于对照组(P<0.05)。治疗后2组炎症因子水平均低于治疗前(P<0.05),且观察组均明显低于对照组(P<0.05)。结论:早期大承气汤灌肠联合肠内营养能够促进临床症状、体征缓解,控制炎症反应,具有积极的临床价值。
Objective: To observe the effect of early Dachengqi soup enema combined with enteral nutrition on severe acute pancreatitis. Methods: From January 2009 to December 2012, 140 cases of severe acute pancreatitis admitted to our hospital were enrolled in the study. Fasting, decompression, rehydration and anti-infective were given routinely. The random numbers The watch method was divided into early Dachengqi soup enema combined with enteral nutrition treatment group and given only enteral nutrition treatment control group of 70 cases, observed after treatment, clinical symptoms, symptom relief time and inflammatory cytokine levels. Results: The body temperature recovery time, abdominal pain relief time, abdominal distension disappearance time and anal exhaust time in the observation group were significantly shorter than those in the control group (P <0.05). After treatment, the levels of inflammatory cytokines in both groups were lower than those before treatment (P <0.05), and the levels in the observation group were significantly lower than those in the control group (P <0.05). Conclusion: Early Dachengqi Decoction combined with enteral nutrition can promote clinical symptoms, relieve symptoms and control inflammatory reaction, which has a positive clinical value.