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该文用放射免疫法及ＥＬＩＳＡ法两种方法测定了２５例脑囊虫病患者血清和脑脊液ＴＮＦα及血清ｓＩＬ－２Ｒ含量。结果：脑囊虫病患者血清ＴＮＦα含量（放射免疫法：１５．６３±１．９１，ｎ＝２１；ＥＬＩＳＡ法：０．６８±０．４５，ｎ＝２５）和血清ｓＩＬ－２Ｒ（ＥＬＴＳＡ法：２３３．９２±１１４．１９，ｎ＝２５）均较正常对照组显著升高（Ｐ＜０．００１）。患者血清ＴＮＦα和ｓｌＬ－２Ｒ间未显示相关关系（ｒ＝－０．２５８，Ｐ＞０．２）。脑脊液中ＴＮＦα含量（放射免疫法：６．５３±２．１４，ｎ＝２１）与对照组相比无显著性差异（Ｐ＞０．０５）。结果提示，ｓＩＬ－２Ｒ和ＴＮＦα均参与脑囊虫病时的系统免疫反应，但两种日子在不同患者间的应答可能存在一定的差异。血清ＴＮＦα含量升高与鞘内性产生无关。
The serum and CSF levels of TNFα and sIL-2R in 25 patients with cerebral cysticercosis were measured by radioimmunoassay and ELISA. Results: Serum levels of TNFα (radioimmunoassay: 15.63 ± 1.91, n = 21; ELISA: 0.68 ± 0.45, n = 25) and serum sIL-2R .92 ± 114.19, n = 25) were significantly higher than the normal control group (P <0.001). Serum TNFα and slL-2R showed no correlation (r = -0.258, P> 0.2). The level of TNFα in CSF (radioimmunoassay: 6.53 ± 2.14, n = 21) showed no significant difference compared with the control group (P> 0.05). The results suggest that both sIL-2R and TNFα are involved in the systemic immune response during cerebral cysticercosis, but there may be some differences between the two days in patient response. The increase of serum TNFα has nothing to do with the intrathecal production.