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目的:观察中药经验方新宫外孕Ⅰ号方加味联合甲氨蝶呤在异位妊娠保守治疗中的临床疗效。方法:选择异位妊娠保守治疗患者60例,采用数字表法随机分为对照组28例、治疗组32例。其中,对照组给予甲氨蝶呤肌肉注射,治疗组在对照组基础上配合口服新宫外孕Ⅰ号加味方。比较两组治疗后的临床疗效、血清人绒毛膜促性腺激素(HCG)水平下降程度、附件区包块大小及盆腔积液深度改变情况。结果:中药煎剂新宫外孕Ⅰ号方加味配合甲氨蝶呤治疗异位妊娠在临床总有效率、降低HCG、缩小附件区包块以及减少盆腔积液方面比单纯使用甲氨蝶呤更具优势,差异具有统计学意义(P<0.05)。结论:中西药结合治疗异位妊娠,不仅能提高保守治疗的成功率、不良反应小,且能更大限度地恢复患者的输卵管功能及生育能力。
Objective: To observe the clinical efficacy of traditional Chinese medicine Fang Fang Xinyuan Oral Pregnancy Ⅰ prescription combined with methotrexate in the conservative treatment of ectopic pregnancy clinical efficacy. Methods: Sixty patients with conservative treatment of ectopic pregnancy were randomly divided into control group (28 cases) and treatment group (32 cases). Among them, the control group was given intramuscular injection of methotrexate, the treatment group on the basis of the control group with oral administration of new ectopic pregnancy No. I side. The clinical curative effect, the degree of serum human chorionic gonadotropin (HCG), the size of the appendage mass and the depth of pelvic effusion were compared between the two groups. Results: Decoction of traditional Chinese medicine decoction of extra-Ectopic pregnancy on the 1st with methotrexate treatment of ectopic pregnancy in the clinical total efficiency, reduce HCG, reduce the size of the annex area and reduce pelvic fluid than the simple use of methotrexate more advantages , The difference was statistically significant (P <0.05). Conclusion: The combination of traditional Chinese and western medicine for ectopic pregnancy can not only improve the success rate of conservative treatment, with less adverse reactions, but also restore tubal function and fertility to a greater extent.