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目的:推广一种面神经损伤模型(绒猴)。方法:将各个非人类灵长类动物绒猴进行3种不同的面神经损伤处理,术后均观察27d,通过图像记录面部运动。结果:两种神经压迫后严重面瘫的模型能够在预估的时间内逐渐恢复到正常水平,而切除神经后则完全失去了面部运动恢复的可能。结论:我们认为压迫所致面神经损伤可以在一个合理的观察窗(4周)内,进行神经营养效果的可能分析。此外,没有迹象表明半面的肌肉有来自于对侧神经的交叉支配,或者其他伴行的神经支配。
Objective: To promote a facial nerve injury model (marmoset). Methods: Three non-human primate animals were treated with facial nerve injury. All the animals were observed for 27 days postoperatively, facial movement was recorded by images. Results: The two models of severe facial paralysis after nerve compression can gradually recover to normal levels in the estimated time, but the nerve recovery completely loses the possibility of facial movement recovery. CONCLUSIONS: We believe that compression of the facial nerve injury may allow a possible analysis of neurotrophic effects within a reasonable window of observation (4 weeks). In addition, there is no indication that half of the muscles have cross-dominance of the contralateral nerve or other accompanying innervation.