论文部分内容阅读
我研究室做了实验性低氧、高碳酸血症动物(狗)的脑脊液的氧及二氧化碳分压变化的实验性研究,发现狗在高碳酸血症伴有低氧血症时的脑脊液的氧分压较动脉血氧分压为高,其机理用Bohr效应解释脉络丛的毛细血管血的氧分压上升,从而使脑脊液的氧分压的升高。即在低氧情况下,依靠脉络丛的代谢及功能来维持和稳定脑脊液的氧分压。据此肺性脑病时,低氧血症并不直接参与肺脑的发生。
My lab did experimental studies on changes in oxygen and carbon dioxide partial pressure in the cerebrospinal fluid of experimental hypoxic and hypercapnic animals (dogs) and found that oxygen in the cerebrospinal fluid of dogs with hypercapnia and hypoxemia Partial pressure is higher than arterial oxygen partial pressure, its mechanism to explain the choroid plexus capillary blood oxygen partial pressure rise with Bohr effect, so that the cerebrospinal fluid oxygen partial pressure increased. That is, under hypoxic conditions, relying on the metabolism and function of the choroid plexus to maintain and stabilize the oxygen pressure of cerebrospinal fluid. According to this pulmonary encephalopathy, hypoxemia does not directly involved in the occurrence of pulmonary brain.