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目的探讨米非司酮治疗子宫肌瘤疗效。方法应用米非司酮10mg自月经d1～d3开始服用,连服3mo为1疗程。用药前、用药后B超测量子宫及子宫肌瘤的三维径线;检测雌孕激素水平、血红蛋白、肝肾功能,观察服药的副作用反应。结果患者治疗期间均闭经,雌孕激素水平维持于增殖早期,血红蛋白上升,子宫及最大肌瘤的平均体积缩小,有显著性差异(P<0.01)。结论米非司酮治疗子宫肌瘤有较好的临床效果。
Objective To investigate the efficacy of mifepristone in the treatment of uterine fibroids. Methods Mifepristone 10mg d1 ~ d3 from the beginning of menstruation, and even served 3mo for a course of treatment. Before treatment, after treatment, B-measure the uterine and uterine fibroids three-dimensional diameter; test estrogen and progesterone levels, hemoglobin, liver and kidney function, observe the side effects of medication. Results All patients underwent amenorrhea during the treatment period. The levels of estrogen and progesterone remained at the early stage of proliferation. The hemoglobin level was increased while the average volume of the uterus and maximal myoma was reduced. There was a significant difference (P <0.01). Conclusion Mifepristone treatment of uterine fibroids have a good clinical effect.