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目的探讨母乳性黄疸婴儿免疫功能水平的变化。方法母乳性黄疸患儿53例,按血清总胆红素(totalbilirubin,TBIL)水平分为重度组(TBIL≥342μmol/L)12例、中度组(256μmol/L0.05);轻度组IgG,IgA,IgM,C3及C4水平与对照组比较差异无统计学意义(P>0.05);重度组治疗后IgG,IgA,IgM,C3及C4水平均高于治疗前,差异有统计学意义(P<0.05)。结论母乳性黄疸患儿TBIL水平≥342μmol/L时,免疫功能低下,早期干预可短期恢复免疫损伤。
Objective To investigate the changes of immune function in infants with breast milk jaundice. Methods 53 cases of breast milk jaundice were divided into severe group (TBIL≥342μmol / L) and moderate group (256μmol / L 0.05). There was no significant difference in the levels of IgG, IgA, IgM, C3 and C4 between the mild group and the control group (P> 0.05). The levels of IgG, IgA, IgM, C3 and C4 in severe group were significantly higher than those before treatment (P <0.05). Conclusion TBIL in children with milk-induced jaundice is associated with poor immune function when TBIL level is above or equal to 342μmol / L. Early intervention may restore immune damage in short term.