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应用免疫组化方法检测３３例脑膜瘤组织中血管内皮细胞生长因子（ＶＥＧＦ）蛋白表达，根据颅脑ＭＲＩ或ＣＴ扫描估计瘤周脑水肿程度。结果：脑膜瘤ＶＥＧＦ表达率７５％，４例可疑表达，表达系数（Ｘ±Ｓ）为２０３±０９６，脑水肿系数（Ｘ±Ｓ）为２３９±１２７，ＶＥＧＦ蛋白表达与ＰＶＢＥ存在相关关系（ｒ＝０７３５２，ｐ＜０００１）。证明ＶＥＧＦ存在于脑膜瘤组织中，在瘤周脑水肿方面发挥重要作用。
Immunohistochemistry was used to detect the expression of vascular endothelial growth factor (VEGF) protein in 33 cases of meningiomas. The extent of peritumoral edema was estimated by MRI or CT scan. Results: The expression of VEGF was 75% in meningioma and 4 in suspicious. The expression coefficient (X ± S) was 2.03 ± 0.96, the coefficient of cerebral edema (X ± S) was 2.39 ± 1.27. VEGF protein There was a correlation between expression and PVBE (r = 07352, p <0001). Vascular endothelial growth factor (VEGF) is found in meningioma tissue and plays an important role in peritumoral edema.