伊维菌素是一种有效的杀灭微丝蚴药物,并能阻断微丝蚴的释出;阿苯达唑则对子宫内各发育阶段的胚胎均有毒性。本研究用伊维菌素合并阿苯达唑治疗盘尾丝虫病,观察合并用药能否产生使雌虫永久性不育的效果。 研究对象为69例男性盘尾丝虫病病人,系加纳森林地区的村民,均住院治疗。在治疗前作详细的全身检查、眼科和心电图检查以及实验室检查;并取4个部位的皮片置等渗 Ivermectin is an effective drug that kills microfilaria and blocks the release of microfilariae; albendazole is toxic to embryos at various developmental stages of the uterus. In this study, ivermectin combined with albendazole treatment of onchocerciasis, the observation of the combination of drugs can produce permanent female infertility effect. The study population consisted of 69 male patients with onchocerciasis who were hospitalized in the Ghanaian forest area. Before treatment for detailed systemic examination, ophthalmology and ECG examination and laboratory tests; and taking four parts of the skin set isotonic