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本文测定了４０例肺癌和５６例肺部良性疾病及５２例其它器官恶性肿瘤患者血清游离唾液酸（ＦＳＡ）。结果表明，肺癌，尤其是肺鳞癌患者ＦＳＡ的含量明显高于肺部良性疾病及其它器官恶性肿瘤患者（Ｐ＜０．０１），（以７７ｍｇ／ｄｌ为阳性界限值）。其对肺鳞癌诊断的阳性率为９３％，特异性为８６．５％。其结果提示，血清ＦＳＡ的测定是肺癌，尤其是肺鳞癌与肺部良性疾病及其它器官恶性肿瘤的一项较为重要的鉴别诊断指标。
This study measured serum free sialic acid (FSA) in 40 patients with lung cancer and 56 patients with benign lung diseases and 52 patients with other organ malignancies. The results showed that the levels of FSA in lung cancer, especially in lung squamous cell carcinoma patients, were significantly higher than those in benign lung diseases and other organ malignancies (P<0.01), with a positive limit of 77 mg/dl. Its positive rate for the diagnosis of lung squamous cell carcinoma is 93%, and the specificity is 86.5%. The results suggest that the measurement of serum FSA is an important differential diagnostic indicator for lung cancer, especially lung squamous cell carcinoma and benign lung diseases and other organ malignancies.