据《British Medical Journal》1994年309卷第6952期报道 为评估早期治疗先天性甲状腺机能减退症是否能完全防止智力的损伤,英国Tillot-son等对1982～1984年全国新生儿普查时发现的先天性甲状腺机能减退症患儿与匹配的正常儿童进行了对比。361名患儿接受了早期治疗,另315名儿童作为对照组。在5岁入学时采用Wechster学龄前和基本智力标准测定智商。诊断时智商和血浆甲状腺素的浓度为一种不连续性相关,其阈值为42.8nmol According to the British Medical Journal 1994 Volume 309, No. 6,952 reported to assess the early treatment of congenital hypothyroidism can completely prevent intellectual damage, the British Tillot-son and other 1982 to 1984 National Neonatal Census found in the innate Hypothyroidism was compared with matched normal children. 361 children received early treatment and 315 children served as controls. Intelligence was measured using Wechster Preschool and Essential Intelligence standards at 5 years of age. Diagnostic IQ and plasma thyroxine concentrations as a discontinuity, with a threshold of 42.8 nmol