目的了解老年２型糖尿病（２ＤＭ）患者尿白蛋白排泄（ＵＡＥ）与视网膜病变（ＤＲ）之间的关系。方法对２４３例老年２ＤＭ患者同时进行了２４ｈＵＡＥ测定、眼底检查和详细的临床资料分析。结果①ＤＲ的发生率随ＵＡＥ的增加而增加，正常、微量和大量白蛋白尿患者，ＤＲ的发生率分别为１１７％、７６０％和８３３％，增殖性ＤＲ发生率分别为１８％、１４７％和３６７％；同样，白蛋白尿的发生率亦随ＤＲ的出现和进展而明显增高；②有白蛋白尿，但不伴ＤＲ的患者，其白蛋白尿常由其他非糖尿病性疾病所致。结论老年２ＤＭ患者ＵＡＥ与ＤＲ的发生密切相关，ＤＲ的存在与否对其白蛋白尿的病因有重要提示价值。 Objective To understand the relationship between urinary albumin excretion (UAE) and retinopathy (DR) in elderly patients with type 2 diabetes mellitus (2DM). Methods 243 cases of elderly patients with DM at the same time 24hUAE determination, fundus examination and detailed clinical data analysis. Results ① The incidence of DR increased with the increase of UAE. The incidences of DR were 117%, 760% and 833% in patients with normal, micro and macroalbuminuria respectively. The rates of proliferative DR were 1  8%, 14  7% and 36  7%; Similarly, the incidence of albuminuria with the emergence and progress of DR was significantly higher; ② albuminuria, but not with DR in patients with albumin Urinary often caused by other non-diabetic diseases. Conclusion There is a close relationship between UAE and DR in the elderly 2DM patients. The presence or absence of DR has important value in the etiology of its albuminuria.