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Two hydrazone ligands(E)-N’-(2-hydroxy-5-methoxybenzylidene)-2-hydroxybenzohydrazide(HLa) and(E)-N?-(3,5-dichloro-2- hydroxybenzylidene)-4-methoxybenzohydrazide(HLb) were prepared and characterized by IR, UV-Vis and 1H NMR spectra. Based on the hydrazone ligands, two new structurally similar vanadium(V) complexes, [VOLaL]·CH3OH(1) and [VOLbL](2), where L is the monoanionic form of benzohydroxamic acid(HL), were prepared and characterized by IR and UV-Vis spectra, and single-crystal X-ray diffraction. Complex 1 crystallizes as the monoclinic space group P21/n, with a = 7.5208(10), b = 15.490(2), c = 20.8929(18) ?, β = 96.373(2)o, V = 2418.9(5) ?3, Z = 4, R = 0.0831, w R = 0.2607 and GOOF = 1.061. Complex 2 crystallizes as the monoclinic space group P21/c, with a = 11.8577(18), b = 16.468(2), c = 12.2288(18) ?, β = 106.064(2)o, V = 2294.7(6) ?3, Z = 4, R = 0.0741, w R = 0.1745 and GOOF = 1.014. X-ray analysis indicates that the complexes are mononuclear vanadium(V) species, with the V atoms located in the octahedral coordination. The hydrazone ligands and the complexes were evaluated for their antibacterial(Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Pseudomonas fluorescence) and antifungal(Candida albicans and Aspergillus niger) activities by MTT(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) method.
Two hydrazone ligands (E) -N’- (2-hydroxy-5-methoxybenzylidene) -2-hydroxybenzohydrazide (HLa) and (E) -N- (3,5-dichloro-2- hydroxybenzylidene) -4-methoxybenzohydrazide HLb) were prepared and characterized by IR, UV-Vis and 1H NMR spectra. Based on the hydrazone ligands, two new structurally similar vanadium (V) complexes, [VOLaL] .CH3OH (1) and [VOLbL] Complex 1 crystallizes as the monoclinic space group P21 / n, with a = 7.5208 (L-the monoanionic form of benzohydroxamic acid (HL), were prepared and characterized by IR and UV-Vis spectra, B = 15.490 (2), c = 20.8929 (18)?, Β = 96.373 (2) o, V = 2418.9 (5)? 3, Z = 4, R = 0.0831, wR = 0.2607 and GOOF = 1.061. Complex 2 crystallizes as the monoclinic space group P21 / c with a = 11.8577 (18), b = 16.468 (2), c = 12.2288 )? 3, Z = 4, R = 0.0741, wR = 0.1745 and GOOF = 1.014. X-ray analysis indicates that the complexes are mononuclear vanadium (V) species, with the V The hydrazone ligands and the complexes were evaluated as their antibacterial (Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Pseudomonas fluorescence) and antifungal (Candida albicans and Aspergillus niger) activities by MTT (3- (4, 5-dimethylthiazol-2-yl) -2,5-diphenyl tetrazolium bromide) method.