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本文采用微分电位溶出法测定２１３例脑梗塞患者血清中Ｃｕ、Ｐｂ、Ｃｄ、Ｚｎ、Ｆｅ、Ｍｎ等微量元素的含量，并与６９例正常人对照。结果表明，各患者组血清中Ｆｅ、Ｍｎ与正常组无明显差别，Ｐｂ、Ｃｄ含量均显著高于正常组（Ｐ＜０．０１）；急性脑梗塞患者（５天内）组Ｃｕ／Ｚｎ比值明显高于对照组（Ｐ＜０．０１），但随时间延长Ｃｕ／Ｚｎ比值逐渐降低；恢复期（３１～６０天）及脑梗塞后遗症两组患者血清Ｃｕ低于对照组（Ｐ＜０．０５），Ｃｕ／Ｚｎ比值远低于对照组（Ｐ＜０．０１），用Ｆｅｉｓｈｅｒ判别分析法比较Ｐｂ、Ｃｄ含量及Ｃｕ／Ｚｎ比值对疾病的作用，证明了Ｐｂ的贡献率为１９．５％，Ｃｄ的贡献率为４１．３％，Ｃｕ／Ｚｎ比值的贡献率为３９．２％，诊断符合率为９６．２５％。
In this paper, the contents of Cu, Pb, Cd, Zn, Fe, Mn and other trace elements in serum of 213 patients with cerebral infarction were determined by the method of differential potentiometry and compared with 69 healthy controls. The results showed that the serum levels of Fe and Mn in each patient group were not significantly different from those in the normal group, and the contents of Pb and Cd were significantly higher than those in the normal group (P <0.01). The Cu / Zn ratio in the patients with acute cerebral infarction (within 5 days) (P <0.01), but the ratio of Cu / Zn decreased gradually with the prolongation of time. The levels of Cu in the convalescence (31-60 days) and cerebral infarction sequelae were lower than those in the control group (P <0.05) ), And the ratio of Cu / Zn was much lower than that of the control group (P <0.01). The effect of Pb and Cd and Cu / Zn ratio on the disease was compared by Feisher discriminant analysis. The contribution rate of Pb was 19.5% , The contribution rate of Cd was 41.3%, the contribution rate of Cu / Zn ratio was 39.2%, and the diagnostic coincidence rate was 96.25%.