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寨卡病毒因其于1947年被首次分离自乌干达的寨卡森林而得名.其后数十年,由于寨卡病毒在人群中的偶发感染及所致的温和病症,一直不太为人所知.直到2015年寨卡病毒在巴西乃至全球大流行,并导致部分胎儿及新生儿罹患先天性脑畸形,如小头症等~([1,2]),引起了整个人类社会的密切关注,被世界卫生组织在2016年2月定义为“全球紧急公共卫生事件”.此前已有研究表明,寨卡病毒是通过靶向作用于
The Zika virus was named for its first isolation from the Zakan forest in Uganda in 1947. It has remained largely unknown for decades afterwards due to the occasional infection of Zika virus in the population and the resulting mild illness It is not until 2015 that Zika virus is pandemic in Brazil and even the whole world, causing some fetuses and newborns with congenital brain deformities, such as microcephaly, etc. ([1,2]), arousing close attention of the entire human society, It was defined by the World Health Organization as “Global Emergency Public Health Incident” in February 2016. Previous studies have shown that Zika virus is targeted by