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有机溶剂——四氢呋喃(THF)的用途日益增多,以往并无中毒病例的报道;作者曾自1967和1980年起进行了现场和动物实验研究。曾有四名从事纺丝实验的研究者,三年来每年使用THF约1个月。由于试验阶段,设备较简陋,估计毒物浓度较高。接触者的自觉症状除有失眠、无力、胃部胀满和腰痛外,对酒的耐受明显降低。此外,齿龈粘膜出血。客观检查最明显的是白细胞数的减少(2000～3000个/mm~3),但无贫血现象,网织红细胞和嗜硷红细胞数属正常;1名尿胆原为强阳性,胆红素指数和酚浊度试验值稍有
The growing use of the organic solvent, tetrahydrofuran (THF), has not been reported in the past for toxic cases; the authors conducted field and animal studies from 1967 and 1980. There are four researchers engaged in spinning experiments, the use of THF for about one month each year for three years. Due to the pilot phase, the equipment is relatively crude and the poison concentration is estimated to be high. In addition to symptoms of contact with insomnia, weakness, stomach fullness and low back pain, alcohol tolerance was significantly reduced. In addition, gum mucosal bleeding. The most obvious objective examination is the reduction of white blood cell count (2000 ~ 3000 / mm ~ 3), but no anemia, reticulocyte and basophilic red blood cell count is normal; a urinary bile is strongly positive, bilirubin index And phenol turbidity test value slightly