1982～1986年在北京地区8个监测点先后检测1905只鼠。结果仅于1985,1986两年从通县、朝阳、某机场、顺义4个点的鼠类中检出6份黑线姬鼠鼠肺肾综合征出血热(HFRS)抗原、带毒率为0.9％～1.9％;检出抗体25份、阳性率为0.6％～11.2％;并以2份抗原阳性鼠肺接种Vero-E_6细胞首次分离出2株HFRS病毒。确定了北京地区HFRS的主要传染源为本地黑线姬鼠,并非由外地传入。从而证实北京地区HFRS自然疫源地的存在。 From 1982 to 1986, 1905 mice were detected at 8 monitoring sites in Beijing. Results Six HFRS antigens of Apodemus agrarinus were detected in 4 mice in Tongxian, Chaoyang, an airport and Shunyi in 1985 and 1986. The incidence of HFRS antigen was 0.9 % ~ 1.9%; 25 antibodies were detected, the positive rate was 0.6% ~ 11.2%; two strains of HFRS virus were isolated from Vero-E_6 cells by two antigen-positive lungs. It was confirmed that the main source of HFRS in Beijing was Apodemus agrarius, which was not introduced from the outside world. Thus confirming the existence of HFRS natural foci in Beijing.