论文部分内容阅读
目的探讨左旋氨氯地平联合坎地沙坦酯片治疗高血压的临床疗效。方法选取2013年3月—2014年3月浑源县人民医院收治的高血压患者369例,随机分为试验组(185例)与对照组(184例)。试验组患者予以左旋氨氯地平联合坎地沙坦酯片治疗,对照组患者予以左旋氨氯地平治疗。观察两组患者临床疗效、治疗前后血压(收缩压、舒张压)变化情况及不良反应发生情况。结果试验组患者总有效率高于对照组,差异有统计学意义(P<0.05);治疗前两组患者收缩压、舒张压比较,差异无统计学意义(P>0.05);治疗后试验组患者收缩压、舒张压低于对照组,差异有统计学意义(P<0.05);两组患者均未发生严重不良反应。结论左旋氨氯地平联合坎地沙坦酯片治疗高血压的临床疗效显著,可有效降低患者血压,且不良反应少。
Objective To investigate the clinical efficacy of levamlodipine combined with candesartan cilexetil in the treatment of hypertension. Methods 369 hypertensive patients admitted to Hunyuan County People’s Hospital from March 2013 to March 2014 were randomly divided into experimental group (185 cases) and control group (184 cases). Patients in the test group were given L-amlodipine combined with candesartan cilexetil, while patients in the control group were treated with levamlodipine. To observe the clinical efficacy of two groups of patients before and after treatment of blood pressure (systolic blood pressure, diastolic blood pressure) changes and adverse reactions. Results The total effective rate of the experimental group was higher than that of the control group (P <0.05). There was no significant difference in systolic pressure and diastolic pressure between the two groups before treatment (P> 0.05) Patients with systolic blood pressure and diastolic blood pressure lower than the control group, the difference was statistically significant (P <0.05); no serious adverse reactions in both groups. Conclusion The clinical efficacy of L-amlodipine combined with candesartan cilexetil acetate in the treatment of hypertension is significant, which can effectively reduce the blood pressure of patients with less adverse reactions.