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目的 通过对山西省肿瘤医院 90年代手术大肠癌患者临床流行病学特点的分析 ,探讨本地区 90年代大肠癌流行规律及变化趋势。方法 统计 1989～ 1999年在该院住院的大肠癌所有病例 ,并进行分析。结果 11年共收治大肠癌 3 0 5 0例 ,其中手术 2 2 46例 ,占 73.6 4% ,男女之比为 1.0 8∶1,男性略高于女性。1991～ 1994年住院人数变化不明显 ,但高于 1989年和 1990年。 1995～ 1999年有逐年上升的趋势。居住在农村的住院患者高于城市 ,但采用 1992年人口为基数 ,计算城市患者住院率为 14.6 6 / 10万 ,是农村 (5 .96 / 10万 )的 2 .46倍。行政划分 8个地区中 ,太原市、晋中地区的住院人数明显高于其他地区。Dukes分期表明 ,住院患者多数为中、晚期。患者年龄从 40岁开始上升 ,5 0～ 70岁为高峰。发病部位以直肠为主 ,共 185 0例占 82 .36 %。组织学类型以腺癌和乳头状腺癌为主 ,占 5 6 .2 3 %和 2 0 .88%。结论 本研究提示 ,应加强对大肠癌预防和临床症状知识的宣传力度 ,提高人群防癌的自我保护意识 ,在城市及高危人群中 ,积极开展普查 ,争取做到早发现、早治疗 ,提高生存率。
Objective To analyze the clinical epidemiological characteristics of surgical colorectal cancer patients in Shanxi Provincial Cancer Hospital in the 1990s, and to explore the prevalence and trends of colorectal cancer in the 1990s. Methods Statistics of all patients with colorectal cancer hospitalized in this hospital from 1989 to 1999 were analyzed. Results A total of 3 050 cases of colorectal cancer were treated in 11 years, of which 2 246 cases were surgery, accounting for 73.6 4%, and the ratio between men and women was 1.0 8:1. Men were slightly higher than women. The number of hospital admissions did not change significantly from 1991 to 1994, but it was higher than in 1989 and 1990. From 1995 to 1999, there was a rising trend year by year. Inpatients living in rural areas were higher than urban residents, but using the 1992 population as the base, the hospitalization rate of urban patients was calculated to be 14.66/100,000, which was 2.46 times that of rural (5.96/100,000). Administrative divisions Among the 8 regions, the number of hospitalizations in Taiyuan and Jinzhong districts was significantly higher than in other regions. Dukes stage shows that the majority of inpatients are middle and late. The patient’s age began to rise from the age of 40, with the peak of 50-70 years old. The site of the disease was mainly rectum, and 185 cases accounted for 82.36%. The histological types were adenocarcinoma and papillary adenocarcinoma, accounting for 56.23% and 20.88%. Conclusion This study suggests that the promotion of knowledge on prevention and clinical symptoms of colorectal cancer should be strengthened, and the self-protection awareness of cancer prevention among the population should be raised. In cities and high-risk populations, active surveys should be conducted to achieve early detection, early treatment, and improve survival. rate.