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目的:分析312例重症肌无力患者病情稳定期的睡眠质量。方法:收集2013年2月—2014年6月第四军医大学唐都医院神经内科门诊就诊的重症肌无力患者,应用匹兹堡睡眠质量指数(PSQI)对患者进行近1月的睡眠质量问卷调查、重症肌无力定量评分表(QMG)进行病情评分,以P<0.05为有统计学意义,对MG患者睡眠质量指数、各因子分进行分析研究。结果:符合重症肌无力诊断标准、知情同意并纳入研究患者共有321例,男156,女165。研究发现,多数重症肌无力患者有睡眠质量问题:性别与睡眠质量、病情评定无相关性(P>0.05);重症肌无力患者睡眠质量问题主要表现为入睡时间、睡眠效率、睡眠障碍、日间功能方面。结论:重症肌无力患者存在睡眠质量差这一问题。改善MG患者肌无力症状的同时,应注重改善患者的睡眠质量。
Objective: To analyze the quality of sleep in 312 patients with myasthenia gravis during stable condition. Methods: Patients with myasthenia gravis diagnosed as neurological outpatient in Tangdu Hospital of the Fourth Military Medical University from February 2013 to June 2014 were enrolled in this study. The patients were assessed with the PSQI questionnaire for nearly 1 month, Muscle weakness quantitative score table (QMG) for disease score, P <0.05 was considered statistically significant, the quality of sleep in patients with MG index, each factor analysis. Results: In line with the diagnostic criteria for myasthenia gravis, informed consent and included in the study a total of 321 patients, male 156, female 165. The study found that the majority of patients with myasthenia gravis have quality of sleep problems: gender and quality of sleep, disease assessment was not related (P> 0.05); sleep quality problems in patients with myasthenia gravis mainly as falling asleep, sleep efficiency, sleep disorders, Functional aspects. Conclusion: Myasthenia gravis has poor sleep quality. Improve the MG patients with myasthenia gravis at the same time, we should focus on improving the quality of sleep in patients.