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本文介绍了血药浓度监测在抢救药物中毒病人中的临床意义和应用。对67例药物中毒病人的分析表明,中毒药物有8类共15种,其中以安定类的中毒发生率最高,占41.8%,其次是抗精神病药物占20.9%,此外还有异烟肼、砷化物,农药类的发生率也较高的同时对28例安定类中毒病人的血药浓度,年龄与性别的关系进行了分析,并列举了一些常见药物的中毒浓度,致死浓度的数据和主要临床症状。最后通过3个典型病例的体征、血药浓度处理及愈后情况具体说明血药浓度监测在抢救中毒病人中的应用。
This article describes the clinical significance of plasma concentration monitoring in the rescue of drug poisoning patients and its application. Analysis of 67 cases of drug poisoning patients showed that there are 15 kinds of poisoning drugs in 8 categories, of which the highest incidence of diazepam was 41.8%, followed by antipsychotic drugs accounted for 20.9%, in addition to isoniazid, arsenic In the meantime, the relationship between plasma concentration, age and sex in 28 stable patients was also analyzed. The poisoning concentration, lethal concentration and clinical data of some common drugs symptom. Finally, through three typical cases of signs, plasma concentration treatment and prognosis of the case of blood concentration monitoring in the rescue of poisoning patients.