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目的 探讨精氨酸 (L - Arg)对心肺转流术 (CPB)后患者红细胞免疫功能的调节作用。 方法 随机选择CPB术后患者 30例 ,分为实验组和对照组 ,对两组患者术后外周血红细胞 C3b受体花环率 (RBC- C3b RR)、红细胞免疫复合物花环率 (RBC- ICR)和循环免疫复合物的动态变化进行了对比研究。 结果 实验组红细胞 C3b受体花环率、红细胞免疫复合物花环率术后明显高于对照组 ,循环免疫复合物也于术后 2周恢复正常。 结论 围术期应用精氨酸可促进 CPB术后患者红细胞免疫功能的恢复。
Objective To investigate the regulatory effect of arginine (L - Arg) on erythrocyte immune function in patients after cardiopulmonary bypass (CPB). Methods Thirty patients with CPB were randomly divided into experimental group and control group. The RBC-C3b RR, RBC-ICR, And the dynamic changes of circulating immune complexes were compared. Results In the experimental group, the ratio of rosette to erythrocyte C3b rosette and rosette of erythrocyte immune complex were significantly higher in the experimental group than in the control group, and the circulating immune complex returned to normal level two weeks after the operation. Conclusion Perioperative application of arginine can promote the recovery of erythrocyte immune function in postoperative patients with CPB.