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目的了解胆管乳头状瘤病的特点，探讨其诊断和治疗方法。方法总结经手术和病理证实的２例资料，并结合国内外文献的复习。结果本病的特征：①病因尚不清楚，胆石和炎症的长期刺激可能与其有关。②组织学上虽呈良性，但有低度恶性倾向。具有多发性、广泛性、恶变率和复发率高的特点。③主要临床表现为黄疸和胆管炎。④术前诊断率低，影像学检查有一定帮助，胆道镜检查有很大价值。结论治疗困难。根治性手术切除是主要治疗方法。肿瘤刮除和胆管引流术后极易复发。化学治疗和激光治疗可能有一定效果。本病是肝移植的一个新指征。
Objective To understand the characteristics of bile duct papillomatosis and discuss its diagnosis and treatment. Methods The data of 2 cases confirmed by surgery and pathology were summarized and combined with the review of literature at home and abroad. Results Characteristics of the disease: 1 The etiology is not yet clear, and long-term stimulation of gallstones and inflammation may be related to it. 2 Although histologically benign, it has a low degree of malignancy. With multiple, extensive, malignant transformation rate and high recurrence rate. 3 The main clinical manifestations are jaundice and cholangitis. 4 The preoperative diagnosis rate is low, imaging studies can help, and choledochoscopy is of great value. Conclusion Treatment is difficult. Radical surgical resection is the main treatment. Tumor scraping and bile duct drainage can easily recur. Chemotherapy and laser treatment may have some effect. The disease is a new indication for liver transplantation.