医院药房中常将磺胺眯与琥珀酰磺胺噻唑混合配成散剂应用,現参考有关書籍,拟定如下分析方法,經过数次实验,結果尚好,特介绍出来,以供有关同志参考。理論依据磺胺眯(SG)的結構上有第一芳香胺基,因此可以直接起重氮化效应;而琥珀酰磺胺噻唑(SST)結構中無第一芳香胺基存在,必需水解掉琥珀酰后,才具有重氮化效应。 Sulfanilamide and succinyl sulfathiazole are often mixed into powder medicaments for use in hospitals and pharmacies. Now refer to relevant books and formulate the following analytical methods. After several experiments, the results are still good and are specially introduced for reference by the relevant comrades. Theoretical Basis Sulfaamide (SG) has a first aromatic amine group on the structure and thus can directly act as a diazotization agent. However, no succinic acid group is present in the succinamide sulfadiazole (SST) , It has a diazotization effect.