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目的:探讨异丙酚复合小剂量咪唑安定麻醉应用于无痛肠镜检查的可行性。方法:260例患者分为无痛肠镜组(A组,n=130)和常规肠镜组(B组,n=130);A组从静脉缓慢注入咪唑安定0.03 mg/kg和异丙酚1~2 mg/kg,睫毛反射或强声刺激反应迟钝即可置入肠镜检查;B组按常规方法进行肠镜检查;专人评估患者的术中和术后恢复情况及术中不良反应。结果:肠镜检查完成率A组高于B组(100%:93%),肠镜检查过程中不良反应A组低于B组,患者满意度A组高于B组。结论:异丙酚复合小剂量咪唑安定麻醉实施无痛肠镜检查是安全可行的。
Objective: To investigate the feasibility of small dose propofol combined with midazolam anesthesia for painless colonoscopy. Methods: 260 patients were divided into painless colonoscopy group (group A, n = 130) and conventional colonoscopy group (group B, n = 130). In group A, midazolam 0.03 mg / kg and propofol 1 ~ 2 mg / kg, eyelash reflex or strong acoustics irritation can be placed in colonoscopy; Group B colonoscopy according to conventional methods; specialist assessment of patients with intraoperative and postoperative recovery and adverse reactions during surgery. Results: The complete rate of colonoscopy in group A was higher than that in group B (100%: 93%). The adverse reaction in group A during colonoscopy was lower than that in group B, and the satisfaction in group A was higher than that in group B. Conclusion: It is safe and feasible to carry out painless colonoscopy with propofol combined with low dose midazolam anesthesia.