论文部分内容阅读
骨髓移植(BMT)在急性白血病(AL)和再生障碍性贫血的治疗中起重要作用,但往往有不少可以接受BMT的患者缺乏适当的供体,在这种情况下,胎肝可作为造血干细胞的一种来源。作者报告2例复发性AL患者使用大剂量环磷酰胺(CY)和全身照射(TBI)后作胎肝移植(FLT)的情况。2例患者均按西雅图拟订的标准确定。FLT前7天用氨甲喋呤(MTX)12mg椎管内注射,前5和4天用
Bone marrow transplantation (BMT) plays an important role in the treatment of acute leukemia (AL) and aplastic anemia, but many patients with BMT often lack adequate donors, in which case fetal liver can serve as a hematopoietic A source of stem cells. The authors report two cases of recurrent AL with high dose cyclophosphamide (CY) and total body irradiation (TBI) for fetal liver transplantation (FLT). Two patients were determined according to the criteria developed by Seattle. Seven days prior to FLT, 12 mg of methotrexate (MTX) was injected intraspinal, for the first 5 and 4 days