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回顾多年文献,发现服用精神药物者往往可造成肥胖,几乎所有的抗精神病药都会引起。此外抗抑郁药、锂盐也可引起。引起肥胖的原因除与精神药物所致食欲亢进、行为镇静和运动减少等有关外,与精神药物对摄食中枢、下丘脑-垂体-肾上腺皮质轴的影响和抗利尿激素所致水分潴留也有关系。可以采取限制进食、增加活动、使用芬氟拉明、换用高效的精神药物、掌握最佳药物剂量、避免多种药合用等综合性措施。
Looking back on many years of literature, it has been found that those taking psychoactive drugs can often cause obesity and that almost all antipsychotics cause them. In addition antidepressants, lithium salts can also cause. The causes of obesity are related to the effects of psychotropic drugs on the feeding center, the hypothalamic-pituitary-adrenal axis and the retention of water due to antidiuretic hormone, in addition to the increase of appetite, psychomotor senescence and decreased exercise. Can take restrictions on eating, increasing activity, the use of fenfluramine, with efficient psychotropic substances, to master the best dose of medicine, to avoid the combination of multiple drugs and other comprehensive measures.