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服用肾上腺皮质激素病人之所以易患感染,据报告是因为粒细胞及单核细胞的机能异常所致。但是仍未彻底阐明皮质激素是通过何种机制阻碍了这些细胞的机能。作者把自静脉血中所分离的粒细胞和单核细胞分别混悬于含有2mM 葡萄糖、1mMCa Cl_2、6mM 铁细胞色素C 和不同浓度的琥珀酸氢皮质酮的HEPES(N—Z—羟乙基—二次乙级二胺—N′-2-Z 磺酸)生理盐水中,在37℃下短期保温后同时添加细胞弛缓素E 5/ml 和刀豆球蛋白50μg/ml,以诱导其过氧化物
The reason why people who take adrenal cortex hormones susceptible to infection, it is reported because of abnormal function of granulocytes and monocytes. However, the mechanism by which these cortical hormones are not yet fully elucidated has hindered the function of these cells. The authors respectively suspended granulocytes and monocytes isolated from venous blood in HEPES (N-Z-hydroxyethyl) phosphate buffer containing 2 mM glucose, 1 mM CaCl2, 6 mM iron cytochrome C and varying concentrations of hydrocortisone succinate - secondary B-diamine-N’-2-Z sulfonic acid) in physiological saline at 37 ℃ after the simultaneous addition of cytochalasin E 5 / ml and Concanavalin 50μg / ml, to induce its past Oxide