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对50例左向右分流先心病并发肺动脉高压患者,进行血浆血栓素B_2(TXB_2)与6-酮-前列腺素F_(1a)(6-keto-PGF_(1a))含量以及二者比值(T/6)的测定。结果发现合并肺动脉高压患者的TXB_2与6-keto-PGF_(1a)的平衡失调,PRA(肾素活性)及A_Ⅱ(血管紧张素A_Ⅱ)也有一定改变。
Thrombin B 2 (TXB 2) and 6-keto-prostaglandin F 1 (1a) (6-keto-PGF 1a) were measured in 50 patients with left-to-right shunt congenital heart disease complicated with pulmonary hypertension. / 6). The results showed that the imbalance of TXB_2 and 6-keto-PGF_ (1a) in patients with pulmonary hypertension had some changes in PRA (renin activity) and A_Ⅱ (angiotensin A_Ⅱ).