论文部分内容阅读
目的 :探讨腹水CK7等单克隆抗体在鉴别原发与转移性卵巢癌腹水中的意义。方法 :对 43例腹水及2 2例手术标本采用免疫组化ABC法进行CK7、MG7、CEA、AB、CK、CK8、EMA、HBME、LCA、VIM单克隆抗体测定。应用SPSS8 0统计软件 ,卡方精确检验分析。结果 :单因素分析表明 :(1)CK7单克隆抗体是鉴别原发性卵巢癌有益的指标。 (2 )原发性和来源于胃转移性卵巢癌腹水标本中MG7表达有显著性差异。 (3)CEA有益于鉴诊断来源肠道的癌性腹水。 (4 )腹水免疫组化结果与手术标本相比无明显差异。结论 :腹水免疫组化细胞学检查有助于提高原发及转移性卵巢腹水的检测率
Objective: To investigate the significance of ascites CK7 and other monoclonal antibodies in the identification of primary and metastatic ovarian cancer ascites. Methods: 43 cases of ascites and 22 cases of surgical specimens were examined by immunohistochemical ABC method for the detection of CK7, MG7, CEA, AB, CK, CK8, EMA, HBME, LCA and VIM monoclonal antibodies. Application of SPSS8 0 statistical software, chi square test. Results: Univariate analysis showed that: (1) CK7 monoclonal antibody is a useful marker to identify primary ovarian cancer. (2) There was a significant difference in MG7 expression between primary and gastric ascites samples from gastric metastatic ovarian cancer. (3) CEA is good for diagnosing cancerous ascites from the intestinal tract of origin. (4) The results of ascites immunohistochemistry no significant difference compared with the surgical specimens. Conclusions: Ascitic fluid immunohistochemistry can improve the detection rate of primary and metastatic ovarian ascites