采用聚氧乙烯单硬脂酸酯（Ｓ－４０）、半合成脂肪酸酯及硬脂酸丙二醇酯为基质，以柠檬醚和碳酸氢钠为泡腾剂，分别制成聚维酮碘栓剂。经对各栓剂的熔点、融变时限、变形温度、起泡时间、泡沫量、泡沫持续时间及药物溶出度等测定，结果认为Ｓ－４０是较理想的泡腾栓基质。 Using polyoxyethylene monostearate (S-40), semi-synthetic fatty acid esters and propylene glycol stearate as matrix, with lemon ether and sodium bicarbonate as effervescent agents, respectively, povidone-iodine suppository. The suppository melting point, melting time, deformation temperature, foaming time, the amount of foam, the duration of the foam and drug dissolution and other measurements, the results that the S-40 is the ideal effervescent plug matrix.