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肾脏疾病合并妊娠时,妊娠会增加肾脏的负担,由于子宫增大的压迫和性激素影响,在解剖上就会有输尿管扩张和阻滞的改变。妊期肾上腺皮质素、肾素、甲状腺素、生长激素的增多,使肾脏功能改变。更重要的是总血容量增加,肾脏肾小球滤过率约比正常人增加50％,肾血流量也约增加25％。醛固酮增多使血清钠潴留。这些妊期的生理性变化使一些肾功能化验数值改变,例如妊期血中尿素氮与肌酐水平分别下降至6～8毫克％与
When kidney disease is combined with pregnancy, pregnancy increases the burden on the kidneys. Due to the increased uterine pressure and the influence of sex hormones, anatomical changes in ureteral dilation and blockade will occur. Pregnancy adrenocorticotropic hormone, renin, thyroid hormone, growth hormone increased, so that changes in renal function. More importantly, the total blood volume increased, renal glomerular filtration rate increased by about 50% than normal, renal blood flow also increased by about 25%. Increased aldosterone serum sodium retention. Physiological changes in these pregnancies cause some changes in renal function tests, such as blood urea nitrogen and creatinine levels during pregnancy decreased to 6 to 8 mg% and